MCQ’S GENERAL PATHOLOGY-GENOME (26/03/2021)

  1. All of the following are part of functional non-protein coding sequences except?

A) Non-coding regulatory RNA

B) Promoter and Enhancer regions

C) Exons

D) Centromere.

Answer: C

2. True statement about histone organization are all except?

A) Histone subunits are negatively charged

B) Nucleosomes are comprised of octamers of histone proteins encircled by 1.8 147 bp DNA loops

C)  Euchromatin is transcriptionally active

D) Histone acetylation opens up the chromatin

Answer: A:- Histones are positively charges and DNA are negatively charges.

3. True about CRISPR/Cas9 system?

A) High precision gene editing system

B) Non-homologous end joining is better than homologous end joining to repair DNA breaks.

C) Cas9 is a dual RNA guided DNA endonuclease enzyme.

D) CRISPR stands for- Clustered regularly interspaced short palindromic repeats.

ANSWER: B: – Homologous end joining is superior to Nonhomologouals end joining.

Please leave your answers in the comment section

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