5 CONDITIONS ASSOCIATED WITH PEUTZ-JEGHERS SYNDROME

PEUTZ-JEHERS SYNDROME IS AN AUTOSOMAL DOMINANT DISORDER. VARIOUS MEDICAL CONDITIONS ARE ASSOCIATED WITH PEUTZ-JEHERS SYNDROME.

Peutz-Jeghers syndrome is an autosomal dominant genetic disorder characterized by the development of benign hamartomatous polyps predominantly in the gastrointestinal tract. Hyperpigmented macules are present in oral mucosa, lips etc. It is associated with SKT11 (LKB1) mutation.

Conditions associated with peutz- jehers syndrome
Conditions associated with peutz- jehers syndrome

Peutz-Jeghers syndrome is associated with various cancers, here are some conditions which when present alerts the clinician to check for an underlying syndrome.

  1. sex cord tumors with annular tubules (SCTAT)
  2. adenoma malignum of the cervix
  3. Sertoli cell tumors (sct)
  4. FEMALE ADENEXAL TUMOR OF PROBABLE WOLFFIAN ORIGIN (FATWO)
  5. OTHER CANCERS SUCH AS CARCINIMA BREAST, COLON, PANCREAS, OVARY AND CERVIX

Watch the video for more info

You may join telegram channel- Pathology mcqs

For pathology mcqs, quizzes, interesting facts and updates – Visit HOME – Pathology for all

Join the Facebook page for daily questions- Pathology mcq

Useful for NEET-SS Oncopathology, DM Histopathology, FRCPath, and Hematopathology fellowships.


by

Tags:

Comments

Leave a Reply

You cannot copy content of this page

%d bloggers like this: