Some gastrointestinal pathogens and their differentiating features. FOR MULTIPLE CHOICE QUESTIONS Gastrointestinal pathogens are very common in routine practice. It takes experience and keen observation to differentiate gastrointestinal pathogens from one another. In case of confusion, go with your ‘GUT’ feeling. Lets look at a few differentiating features of Giardia lamblia, Cryptosporidium parvum and Isospora belli. GIARDIA LAMBLIA: Pear shaped trophozoites with 2 ovoid nuclei, present in the luminal surface. They are 10-15 microns in length and 5-9 microns in width. GIARDIA IS SEEN IN THE LUMINAL SURFACE CRYPTOSPORIDIUM IS SEEN ATTACHED TO ENTEROCYTES LIKE SMALL BEADS. 2. CRYPTOSOPORIDIUM PARVUM In tissue biopsies, 2 – 5 μm basophilic round bodies are seen protruding from the apex of enterocytes (“blue beads”) within the cell membrane. Parasites bulge out of apex of epithelial cells ISOSPORA IS LARGEST AMONG THE THREE. IN CONTRAST TO GIARDIA AND CRYPTOSPORIDIUM – ISOSPORA DOES NOT HAVE AN APICAL LOCATION, INSTEAD LOCATED IN THE TIP OF VILLI. 3. ISOSPORA BELLI Oocysts are generally ovoid to ellipsoid in shape, range from 10-40µm in length by 10-30µm in width. Cysts are present in PARASITO-PHOROUS VACUOLE. Does not have an apical location. FOR MULTIPLE CHOICE QUESTIONS Look below for a quick summary PARIS SYSTEM FOR REPORTING URINARY CYTOLOGY MCQs by Pathology MCQs 22 Mar 2022 Breast Pathology MCQ 1 by Pathology MCQs 12 Mar 2022 CNS Pathology case based MCQs-2 by Pathology MCQs 23 Feb 2022 Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...