Here are a few images, all you got to do is to guess the type of genetic mutation in the leiomyoma just based on the morphology.
What do you think the type of leiomyoma is?
A. Leiomyoma with bizzare nuclei
B. Fumarate hydratase deficient leiomyoma
C. Cellular leiomyoma
D. Mitotically active leiomyoma
The correct answer is B- Fumarate hydratase deficient leiomyoma.
Option A: Leiomyoma with bizzare nuclei does not have an eosinophilic nucleoli.
Option C: Cellular leiomyoma is more cellular than the adjacent myometrium.
Option D: Mitotically active leiomyoma has a mitosis of > 4-10/ HPF