Pathology MCQs for various entrance exams

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1. Which of the following immunohistochemical stains will likely be negative in adrenal cortical carcinomas?

A. Inhibin-A

B. Vimentin

C. Synapcophysin

D. Chromogranin A

E. CandD

2. Which of the following factors does not significantly influence prognosis in neuroblascom

A. Age <l year

B. Lymph node status at the time of diagnosis

C. Lesions outside the adrenal gland

D. Expression of Trk gene

E. DNA hyperdiploidy

3. Syndromes associated with pheochromocytoma include all of the following EXCEPT:

A. Beckwith-Wiedemann syndrome

B. MEN type II

C. von Hippel-Lindau disease

D. Von Recklinghausen disease

E. Sturge-Weber syndrome

4. Which of the following statements regarding parathyroid adenoma is TRUE?

A. It is the second most common cause of primary hyperthyroidism.

B. Most occur during the 7th and 8th decades of life.

C. Men are more commonly affected than women.

D. It is less commonly associated with MEN syndromes than primary chief cell hyperplasia.

E. It is more commonly seen in the superior glands.

5. Adamantinomatous and papillary craniopharyngiomas differ in all respects EXCEPT:

A. Age of affected patients

B. Cystic vs solid nature

C. Recurrence risk

D. Degree of adherence to surrounding structures

E. Treatment

6. The inflammatory infiltrate seen in Hashimoto thyroiditis is best characterized by?

A. Mixed acute and chronic inflammation

B. Dense lymphoid and plasmacytic infiltrate with large follicles and prominent germinal centers

C. Scant lymphoid infiltrate, more prominent within the interlobular fibrous band

D. Lymphoid infiltrate consisting primarily ofB cells versus T cells

E. Primarily IgA-containing plasma cells with lambda light chains

7. All of the following molecular alterations are commonly associated with papillary thyroid carcinoma EXCEPT:

A. Aneuploidy in 95% of cases

B. Rearrangement of RET oncogene

C. Rearrangement ofTRKI

D. RAS mutation in the follicular variant

E. Point mutations of BRAF gene

Endocrine pathology MCQs

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Endocrine pathology MCQs

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