Normal Thymic Histology and IHC

Welcome to your Normal Thymic Histology and IHC

Which of the following immunohistochemical markers is used to identify thymic epithelial cells?

A) CD3

B) CD20

C) Cytokeratin

D) CD68

E) CD34

None

Which of the following cell types in the thymus is primarily responsible for the positive selection of T lymphocytes?

A) Thymic medullary epithelial cells

B) Thymic cortical epithelial cells

C) Hassall's corpuscles

D) Dendritic cells

E) Macrophages

None

Which of the following is TRUE regarding the normal expression of CD1a in the thymus?

A) CD1a is expressed by thymic epithelial cells.

B) CD1a is expressed by mature T cells in the thymus.

C) CD1a is expressed by cortical thymocytes.

D) CD1a is expressed only in the thymic medulla.

E) CD1a expression is absent in normal thymic histology.

None

Which immunohistochemical marker is commonly used to identify immature T lymphocytes in the thymic cortex?

A) CD20

B) CD68

C) CD3

D) CD4

E) TdT

None

What is the function of Hassall's corpuscles in the thymic medulla?

A) Site of T-cell positive selection

B) Responsible for B-cell maturation

C) Involved in T-cell negative selection

D) Induction of regulatory T cells

E) Secretion of thymopoietin

None

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