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Robbins pathology chapter 1 mcq- The cell

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Pathology MCQs

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Welcome to your Robbins chapter 1- The cell

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1.

All of the following are part of functional non-protein coding sequences except?

A. Non-coding regulatory RNA

B. Promoter and Enhancer regions

C. Exons

D. Centromere

2.

True statement about histone organization are all except?

A. Histone subunits are negatively charged

B. Nucleosomes are comprised of octamers of histone proteins encircled by 1.8 147 bp DNA loops

C. Euchromatin is transcriptionally active

D. Histone acetylation opens up the chromatin

3.

True about CRISPR/Cas9 system except?

A. High precision gene editing system

B. Non-homologous end joining is better than homologous end joining to repair DNA breaks.

C. Cas9 is a dual RNA guided DNA endonuclease enzyme.

D. CRISPR stands for- Clustered regularly interspaced short palindromic repeats.

4.

Which of the following is not matched correctly?

A. Lysosome- Autophagy

B. Endosomal vescicles- shuttle internalized materials outside the cell

C. Proteosome- Degrades tagged proteins

D. Peroxisomes- Breaks down very long chain fatty acids.

5.

Most abundant cytoskeletal protein, 5-9 nm in diameter is

A. Actin

B. Myosin

C. Desmin

D. Laminin

6.

All are true regarding protein synthesis except?

A. Membrane bound ribosomes in the RER translate mRNA.

B. Chaperones assist folding of proteins

C. From the RER, proteins and lipids destined for other organelles or extracellular export are shuttled into the Golgi apparatus

D. O- linked oligosaccharides are converted into N- linked Oligosaccharides in golgi apparatus.

7.

All are true about receptors with tyrosine kinase activity except?

A. Downstream phosphorylation is a common pathway of signal transduction

B. Changes in receptor geometry can stimulate intrinsic receptor protein kinase activity

C. The cellular homologue of the transforming protein of the Rous sarcoma virus, called Src, is the prototype of this family.

8.

Which one is matched correctly?

Add description here!

A. EGFR- synonymous to ERB-B2

B. Her-2-neu -ERB-B1

C. TGF-beta- Inflammatory cytokine

D. Hepatocyte growth factor- Scatter factor.

9.

Which of the following is false about collagen ?

A. Collagen I,V and XI are heterotrimers

B. Marfan syndrome is caused by defects in collagen

C. Helix formation occurs in the golgi apparatus

D. Cross-linking occurs in the extracellular space

10.

Correctly matched with organ and stem cell niche are all except?

A. Intestine- crypts

B. Eyes- limbus of cornea

C. Brain- periventricular zones

D. Bone marrow- Paratrabecular area

11.

Which is the true statement?

A. Rb gene is the key regulator of G2M cell cycle transition.

B. Rb is active in hypophospholylated state

C. MDM2 protein activates p53

D. p53 activation leads to cell cycle progression

1 out of 11

1 2 3 4 5 6 7 8 9 10 11

Time’s up

Time is Up!

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6 responses to “Robbins pathology chapter 1 mcq- The cell”

Dr. Tarun Roy

19 Nov 2022

Hepatocyte growth factor is also known as scatter factor.
Ref: https://en.wikipedia.org/wiki/Hepatocyte_growth_factor

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Pathology MCQs

19 Nov 2022

Yes that is correct!!

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Aashish K

30 Dec 2022

Q3 should be ‘All are true EXCEPT’ i suppose

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1. Pathology MCQs
  
  30 Dec 2022
  
  Yes, that’s right!! Corrected.
  
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Anonymous

16 Feb 2024

Excellent questions..

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Ashwini Makode

23 Apr 2024

Questions covered almost all the topics,very nice

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