Pathology MCQs for various entrance exams

Welcome to your Robbins chapter 7 : MCQs Neoplasia
Wait for the answers to appear after each selection. This is not a graded quiz.

Identify the FALSE statement regarding RAS pathway

A. RAS is usually in the excited signal transmitting stage when it is bound to GTP

B. PTEN protein inhibits PI3K

C. GAP proteins accenuate RAS activation

D. NF 1 Inhibits the downstream action of RAS

2. True about oncogene addiction

A. Tumorgenesis is highly dependent on the activity of one oncoprotein

B. Increased expression of oncogenes

C. Accumulayion of a particular intermediate metabolite resulting in tumorgenesis

D. Inability for the damaged cell to result in cell death

3. All of the following are activities of MYC as an oncogene EXCEPT?

A. MYC upregulates the expression of rRNA

B. MYC can upregulate warburg effect

C. MYC acts by inhibiting p16 protein

D. MYC activates certain cyclins

4. Which of the following is TRUE?

A. p21 is induced by tumor supressor TGF - Beta

B. p27 is induced by p53

C. p16 promotes inhibitory effects of P53

D. p14 increases p53 levels

5. Identify the FALSE statement regarding Epithelial mesenchymal transition (EMT)

A. Epithelial mesenchymal transition is controlled by SNAIL and TWIST proteins

B. E-Cadherin expression is enhanced during EMT

C. Downregulation of epithelial markers and upregulation of mesenchymal markers

D. Integral to breast and pprostrate cancers

· 6 Dec 2021