SOFT TISSUE TUMORS -QUIZ Welcome to your SOFT TISSUE TUMORS IHC -QUIZ 1. Which immunohistochemistry profile would support the diagnosis of synovial sarcoma when differentiating it from other spindle cell malignancies? (a) CK +, EMA +, S100 +, HMB-45 -, desmin -, CD99 +, CD117 -, H-caldesmon - (b) CK -, EMA -, S100 -, HMB-45+, desmin -, CD99 -, CD117 -, H-caldesmon - (c) CK +, EMA +, S100 +, HMB-45 +, desmin +, CD99 -, CD117 -, H-caldesmon - (d) CK-, EMA -, S100 +, HMB-45 -, desmin +, CD99 +, CD117 +, H-caldesmon + (e) None of the above 2. When differentiating round cell malignancy, which of the following is correct? (a) Small cell carcinoma: CK+, synaptophysin+, CD56 +, CD45 -, PLAP -, CD99-, desmin - (b) Lymphoma: CK-, CD56 -, CD45+, PLAP -, CD99-, CD117-, desmin - (c) Rhabdomyosarcoma: CK +, CD56 +, CD45 -, CD99 +, CD117-, desmin +, myogenin - (d) All of the above (e) A and B only 3. Which is a true statement/s regarding spindle cell melanoma? (a) It usually stains positive for S100. (b) It usually stains positive for HMB45. (c) FNA is usually hypercellular with many dissociated cells and rare clustering. (d) All of the above. (e) A and C only. Time is Up! Time's up Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...