TEST YOUR KNOWLEDGE- TRANSFUSION REACTIONS., Posted on 15 Jul 202115 Jul 2021 by pathologymcqs Welcome to your TEST YOUR KNOWLEDGE- TRANSFUSION REACTIONS 1. A patient develops sudden back pain, fever, and red urine 10 minutes into the transfusion of a unit of RBCs. Which one of the following should be on the top of your differential diagnosis?A. Febrile nonhemolytic transfusion reaction.B. Transfusion-related acute lung injury.C. Acute hemolytic transfusion reaction.D. Anaphylactic transfusion reaction.E. Transfusion-related sepsis. 2. A stable 35-year-old white male patient develops urticaria and acute dyspnea requiring emergent intubation 15 minutes into the transfusion of 1 U fresh frozen plasma. His pretransfusion vital signs are heart rate (HR), 70 beats/min; respiratory rate (RR), 18/min; blood pressure (BP), 125/80 mm Hg; temperature (T), 36.8°C; and O2 saturation, 99% on room air. Postreaction vital signs are HR, 130 beats/min; RR, 30/min; BP, 90/50 mm Hg; T, 36.8°C; and O2 saturation, 75% on room air. He had a similar reaction to plasma in the past, also requiring intubation. Which of the following should be at the top of your differential diagnosis as a cause of the transfusion reaction?A. Acute hemolytic transfusion reaction.B. Anaphylactic transfusion reaction.C. Transfusion-associated circulatory overload.D. Transfusion-related acute lung injury.E. Transfusion-related sepsis. 3. According to expert opinion, which one of the following is the pathophysiology of a febrile nonhemolytic transfusion reaction (FNHTR) after transfusion of a prestorage leukoreduced blood component?A. Passive transfusion of cytokines or recipient cytokine response to transfusion.B. Passive transfusion of anti-HLA antibodies for which the patient has the cognate antigen.C. Passive transfusion of biologically active lipids.D. Passive transfusion of cells carrying an RBC antigen for which the patient makes an alloantibody.E. Passive transfusion of plasma proteins to which the recipient makes IgE antibodies. 4. Which one of the following is part of the diagnostic criteria for transfusion-related acute lung injury (TRALI)?A. Onset of symptoms within 24 hours of transfusion.B. Presence of fever.C. Leukopenia.D. No evidence of left atrial hypertension.E. Presence of irreversible lung injury. Time is Up! Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading... Related Author: pathologymcqs Daily MCQ's and updates will be posted for various entrance exams View All Posts
