Tag: Acute myeloid leukemia with NPM-1 mutation

  • 10 Key points to remember in NPM-1 mutated AML (Acute myeloid leukemia)

    10 Key points to remember in NPM-1 mutated AML (Acute myeloid leukemia)

    Acute myeloid leukaemia (AML) with mutated NPM1 carries mutations that usually involve exon 12 of NPM1. Here are some key points to remember. 1. There is a female predominance in this type of AML. 2. There is a strong association between both acute myelomonocytic and acute monocytic leukaemia and NPM1 mu­tation. 3. Charactistic cup-shaped blasts…

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