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Tag: Acute myeloid leukemia with NPM-1 mutation
Acute myeloid leukaemia (AML) with mutated NPM1 carries mutations that usually involve exon 12 of NPM1. Here are some key points to remember. 1. There is a female predominance in this type of AML. 2. There is a strong association between both acute myelomonocytic and acute monocytic leukaemia and NPM1 mutation. 3. Charactistic cup-shaped blasts…