HEMOPHILIA B LEYDEN- A rare form of FIX deficiency HEMOPHILIA B LEYDEN is a rare form of FIX deficiency Here are some key points to be noted regarding Hemophilia B Leyden. It is a rare form of FIX deficiency, hemophilia B Leyden, undergoes postpubertal phenotypic resolution.Patients with this condition present with hemophilia B in early childhood, with FIX activity ranging from less than 1% to 13% of normal. Plasma levels rise to as high as 70% of normal after the onset of puberty with resolution of bleeding complications.Mutations in hemophilia B Leyden have been identified in the promoter region of the FIX gene, within which a consensus sequence for steroid receptor binding is located. REVIEW QUESTION- A QUESTION FROM DM HEMATOPATHOLOGY PGIMER ENTRANCE CLICK TO REVEAL THE ANSWER ANSWER is C: Steroid receptor is involved in the pathogenesis. Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...