Common ANA immunofluorescence patterns
Systemic lupus erythematosus (SLE) is an autoimmune disorder involving almost all organ systems. Autoantibodies in SLE are directed towards various cell components. Most common antibody encountered in SLE is ANA (anti-nuclear antibodies) directed towards the nuclear components (DNA, RNA, nucleolus etc). Immunofluorescence is a technique used to highlight antibodies towards a specific cell component with […]
Molecular pathogenesis of ovarian epithelial tumors.
Molecular progression of serous ovarian tumor. Borderline low and high grade 1.Molecular progression of low grade ovarian serous tumors. There is data to suggest progression from serous cystadenoma / cystadenofibroma with BRAF / KRAS mutations → SBT (serous borderline tumor) → LGSC (Low grade serous carcinoma) ; however, this is still controversial 2. Molecular progression of high […]
GENERAL PATHOLOGY MCQ’S- APOPTOSIS.
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GENERAL PATHOLOGY MCQ- IRREVERSIBLE INJURY-NECROSIS updated answers.
QUESTION: Which of the following statements is false regarding necrosis? A) Necrosis is always pathological B) Caseous necrosis is most common in the brain C) Caseous necrosis is characteristic of a tubercular granuloma D) Morphologically, necrotic cells show increased eosinophilia in a hematoxylin and eosin staining Answer: B- Liquefactive necrosis occurs in the brain. Caseous […]