Molecular markers in non small cell lung carcinoma

Welcome to your Molecular markers in non small cell lung carcinoma

Which of the following oncogenes does crizotinib inhibit apart from ALK (asked in AIIMS SR/INI-SS exam 2021)

A. ROS-1

B. MET

C. BRAF

D. PDL-1

Identify the correct match?

A. 20 year old female , non smoker- RAS mutation

B. 20- year old female smoker- EGFR mutation

C. 20-year old female , non smoker ALK mutation

D. All are true

Which of the following oncogenes does alectinib inhibit apart from ALK ? (Potential INI-SS question)

A. C-MET

B. RET

C. ROS-1

D. PI3CA

Identify the INcorrect match?

A. 50- year old man with history of heavy smoking possibly squamous histology- PDL 1 mutation

B. Micropapillary adenocarcinoma of the lung in a 40-year old non smoking female- EGFR mutation

C. Mucin predominant adenocarcinoma in 35-year smoker male- RAS mutation

D. All are correct

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