Posted in General pathology

Characteristics of Epithelial-Mesenchymal transition

EMT- Epithelial mesenchymal transition
1. It is integral to breast and prostrate cancers. 
2. EMT is controlled by SNAIL and TWIST proteins. 
3. Down regulation of epithelial markers and upregulation of mesenchymal markers. 
4. E cadherin    expression is slilenced
5. Strong migratory potential
Epithelial Mesenchymal Transition

EMT- Epithelial mesenchymal transition

  1. It is integral to breast and prostrate cancers.
  2. EMT is controlled by SNAIL and TWIST proteins.
  3. Down regulation of epithelial markers and upregulation of mesenchymal markers.
  4. E cadherin expression is slilenced
  5. Strong migratory potential