Review question 1- APML Welcome to your Review question 1- APML A 40- year old female presented to the emergency with fatigue for 1 week and heavy nosebleed for the past few hours. CBC - Hb- 7.5g/dl WBC- 50 x 109 per liter Platelet count - 10,000 per microliter Peripheral smear shows the finding in the image. Which of the following is false regarding this condition? False about this condition? A. Most commonly associated with PML-RARA fusion detectable by in- situ hybridization. B. FLT3-ITD mutations are also common with this morphology. C. ZBTB16-RARA fusion carries a worse prognosis due to treatment resistance D. STAT5B-RARA fusion also carries a worse prognosis due to treatment resistance. Time is Up! Time's up Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...