Molluscum Contagiosum vs Myrmecia Wart Histopathology guide with virtual slides
Two viral skin lesions. Two distinct patterns of inclusion bodies. Can you distinguish them on histology?
Molluscum contagiosum & myrmecia wart virtual slides
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Molluscum contagiosum vs myrmecia wart: FAQs
How do you tell molluscum contagiosum from a myrmecia wart on histology?
Use the 2-step rule: architecture first, inclusions second. Molluscum shows a central crater with a lobulated epidermal proliferation and relatively uniform Henderson–Patterson bodies. Myrmecia shows inward-growing “ant-hill” architecture with coarse, irregular, variable eosinophilic inclusions.
What are Henderson–Patterson (molluscum) bodies?
Large, relatively uniform intracytoplasmic inclusion bodies of molluscum contagiosum — eosinophilic in deeper cells and basophilic toward the surface. As they enlarge they compress the nucleus into a crescent shape.
Which virus causes myrmecia wart?
Human papillomavirus type 1 (HPV 1). It is a deep, painful, often solitary wart of the palm or sole; parakeratotic columns and haemorrhage correspond to the clinical black dots.
What are the main histologic mimics?
Keratoacanthoma (crater with keratin plug, no viral inclusions), herpes simplex / VZV (Cowdry A intranuclear inclusions), orf / milker’s nodule, verruca vulgaris (koilocytes), and Cryptococcus / Histoplasma (yeasts on PAS/GMS).
Molluscum contagiosum vs myrmecia wart histopathology with virtual slides and a free PDF — built for NEET-SS and INI-SS (DM Histopathology / Oncopathology) aspirants, FRCPath Part 1 and Part 2 histopathology candidates, MD/DNB pathology residents, and APCP board preparation or pathology board preparation.
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