Breast pathology – IHC MCQs Welcome to your Breast pathology - IHC MCQs 1. All of the following are true regarding A typical lobular hyperplasia/lobular carcinoma in situation except? A. Loss of E-cadherin B. Presence of mucin vacuoles C. Loss of E-cadherin and mucin vacuoles are used as a criteria for diagnosis D. All are true 2. Which of the following immunohistochemistry profiles favour paget's disease over squamous cell carcinoma in situ( bowens disease)? A. Her2 /Cam 5.2/GCDFP-15 -Positive B. HMWK positive and GCDFP-15 negative C. PAS and mucicarmine negative D. Melan A positive and HMWK positive 3. All are true regarding immunohistochemistry of breast carcinoma except? A. 10-30% of ductal breast carcinoma are positive for Her-2 B. GATA 3 is a nuclear marker seen on >90% of breast carcinoma C. SOX 10 expression is enriched in triple negative breast cancers D. HMWK (P63 and p40) are positive in microglandular adenosis Time is Up! Time's up Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...