A 29-year-old man presents to his physician for partner screening. The complete blood cell count (CBC) and ferritin level are shown in Table 1. (Image 1)shows the hemoglobin fractions identified on high-performance liquid chromatography (HPLC). Which one of the following is the most likely diagnosis?
Table 1:
Image: 1
1 out of 10
A 23-year-old pregnant woman at 12 weeks’ gestation presents to her obstetrician for prenatal screening. A CBC and a ferritin level are shown in Table 2. Image 2- shows hemoglobin fractionation by HPLC. Which one of the following is the most likely diagnosis?
2 out of 10
A 23-year-old woman who is 12 weeks pregnant presents to her obstetrician for prenatal screening. A CBC and a ferritin level are shown in table 3 . Image 3 shows hemoglobin fractionation by HPLC. Which one of the following is the most likely diagnosis?
3 out of 10
A 27-year-old Thai man with no significant medical history presents to a genetic counselor for partner testing. Which one of the following diagnoses is most consistent with the complete cell blood count in Table 4. and HPLC chromatogram (Image 4)?
4 out of 10
Identify the incorrect match?
5 out of 10
Which one of the following is the most likely diagnosis?
Which one of the following hemoglobins represents the hemoglobin at the arrowhead shown the image?
Which one of the following clinical syndromes is associated with deletion of four α-globin genes?
6 out of 10
Cellulose acetate electrophoresis (Image 7 )performed at pH 8.2 is a method used to separate which one of the following pairs of hemoglobins?
7 out of 10
A 23-year-old African-American woman is seen by her obstetrician for a routine prenatal visit. A CBC was performed and is shown in Table 8. Results of hemoglobin electrophoresis are shown in Figure 8. The sickle solubility test result was negative. Which one of the following is the best diagnosis based on these results?
8 out of 10
A 34-year-old pregnant African American woman is seen in her obstetrician’s office and undergoes hemoglobinopathy screening. The alkaline and acid hemoglobin electrophoreses are shown in Image 9. The sickle solubility test is positive. Which one of the following cell components would be present in the RBC inclusion of this patient?
r
9 out of 10
Which is not considered as a differential diagnosis of this HPLC
10 out of 10
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