P53 Signature Lesion in Ovarian Tumors: Histological Features and Progression

Precursor lesions of high grade serous ovarian tumors. Their progression and histological features summarized.

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This lesion is p53 signature lesion.

Answer is D

Epithelium has a normal histology

Mutant pattern p53 staining with at least 12 cells in a row

Low ki67 index

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