FEMALE GENITAL TRACT QUIZ- OVARY (ANSWERS) Posted on 28 May 2021 by pathologymcqs Quiz on- Ovarian tumors. Each correct answer carries 5 marks. Answers will appear after each selection. Good luck!! What is the pTNM stage according to AJCC 8th edition of a malignant ovarian tumor. Both ovaries are involved and uterine implants are present. No nodal involvement or no other organ involvement is seen.A. pT1c N0 M0, Stage ICB. pT1c N0 M1b, Stage IVBC. pT2a N0 M0 Stage IIBD. pT3c N0 M1b, Stage IVB Which of the following precursors is marked correctly with the type of ovarian cancer arising from it?A. Serous borderline tumor- High grade serous carcinomaB. Benign Brenner tumor- Mucinous carcinomaC. Endometriosis- Low grade serous carcinomaD. All are true Most common site of Serous tubal intraepithelial carcinoma (STIC) lesion is?A.FimbriaeB.AmpullaC.IsthmusD.None Which of the following appearances of high grade serous carcinomas of ovary should raise suspicion and mandate testing for BRCA1 mutationSolidMucinousClear cellPapillary Which of the following is genes is implicated in the progression of Serous borderline ovarian tumor to low grade serous carcinoma?A. P53B. RASC. ARIDAD. BRCA In which of the following ovarian epithelial tumors is trastuzumab tried as a therapy?A. MucinousB. TranstionalC. Clear cellD. Endometrioid PARP- inhibitors are used in the therapy of which of the following ovarian epithelial tumorsClear cell carcinomaHigh grade serous ovarian epithelial tumorsTransitional cell tumorsMucinous carcinoma Which of the following tumors is shown in the picture? On IHC staining, it has FOX L2 and Inhibin positive. (Reticulin stain shown in the picture)Add description here!Granulosa cell tumorThecomaFibromaSertoli-leydig cell tumor A 55- year old female presents with post menopausal bleeding. An endometrial tumor was identified (morphology in image. She had a history of ovarian tumor resection 2 years back. Which of the following options represent the ovarian tumorLeydig cell tumorSerous borderline tumorGranulosa cell tumorChronic Endometriosis 20-year-old woman who presented with abnormal uterine bleeding and abdominal pain. An adnexal mass was identified and surgical excision was performed. Histopathology is shown in the picture. Which of the following is true regarding the tumor?A. FOXL-2 mutations is present in majority of casesB. 50% tumors are bilateralC. Inhibin is a useful marker to differentiate this tumor from thecomas.D. Inhibin negative tumors are also calretinin negative Choriocarcinoma does NOT react immunohistochemically with which of the following?A. InhibinB. hCGC. Human placental lactogenD. Pancytokeratin The finding shown in the picture is characteristic of which ovarian tumor?Leydig cell tumorSertoli cell tumorGranulosa cell tumorsFibroma What differentiates a malignant Brenner tumor from an ovarian transitional cell tumor?A. History of a primary bladder tumorB. Mucinous metaplasiaC. Presence of malignant components of transitional cells alone without benign or borderline componentsD. All of the above All of the following are associated with Peutz- Jehers syndrome except?A) Sertoli cell tumorsB) Adenoma malignumC) Sertoli leydig cell tumor with annular tubules (STCAT)D) Brenner tumor True regarding the ovarian tumor shown in the picture is?A. Does not have a favorable prognosisB. Presence of severe atypiaC. Presence of epithelial cells in sheetsD. Presence of psammoma bodies in atleast >75% papillae in the rest Mixed malignant germ cell tumors of ovary are most commonly composed of which of the following componentsA. Dysgerminoma and yolk sac tumorB. Yolk sac tumor and embryonal carcinomaC. Dysgerminoma and embryonal carcinomaD. None of the above Identify the grade of teratoma, if the tumor contains moderate embryonal neural tissue >1 to < 4 low power fields?Grade IGrade IIGrade IIIImmature neural tissue is not important in the grading of teratoma Which of the following laboratory parameters are increased in this tumorAFPCA-125hCGPLAP A 40 - year old female presented with lower abdominal pain. On CT a right ovarian mass, the mass was excised, an H and E stained section is shown below. Which of the following is true regarding this tumor? A) Serum hCG and AFP are elevated in all tumorsB) They are typically negative for CD30, SOX2, and glypican-3C) OCT3/4 and glypican -3 are positive on IHCD) Granulomatous reaction is present in 100% of cases Germline truncating mutations in which of the following have been reported in sertoli and leydig cell tumor?TP53DICER1KRASBRAF Which of the following ovarian tumor shows this characteristic findingGranulosa cell tumorLeydig cell tumorSertoli cell tumorDysgerminoma Time is Up! Related Author: pathologymcqs Daily MCQ's and updates will be posted for various entrance exams View All Posts
Very interesting,so informative