Female Genital Tract- Uterus MCQs Welcome to your Female Genital Tract- Uterus MCQs-Sample 1. A 55-year-old woman has a hysterectomy for persistent bleeding. On gross examination you see a 2-cm polypoid mass with a villous surface. The cut surface is white, spongy and cystic. Microscopically the surface of the lesion has broad, dub-shaped papillae of stroma covered by proliferative phase endometrial cells. The stroma consists of bland cells that resemble fibroblasts and benign endometrial stromal cells. What is the diagnosis? Adenomyoma Atypical polypoid adenoma Adenofibroma Benign polyp Adenomatoid tumor 2. Which of the following can be seen in atypical hyperplasia? Architectural pattern may be simple or complex. Metaplastic changes may be present in any type of hyperplasia (particularly the morular variant of squamous metaplasia). True nuclear stratification (2-4 cells thick) with loss of polarity usually present and ofi:en more marked than in complex hyperplasia without atypia. Atypical cells tend to be enlarged; nuclear-cytoplasmic ratio is increased; nuclei large, hyperchromatic, and pleomorphic (tend to be more rounded than oval); nuclear membranes usually irregular·and thick; nucleoli prominent All of the above 3. According to the latest WHO classification of female genital tract tumors (2020), which of the following variants of leiomyoma is an addition? Symplastic Fumarate hydratase deficient Anaplastic Bizzare Pleomorphic 4. A 51 year old woman presented with vaginal bleeding and workup revealed a large uterine mass. Hysterectomy and bilateral salpingo-oophorectomy is performed. Pathology is consistent with a low grade endometrial sarcoma. Which of the following statements is false? CD10 is negative in tumor cells ER and PR positive in tumor cells h-Caldesmon is negative in tumor cells JAZF1-SUZ12 mutation is most commonly seen 5. True statement about the recently proposed molecular classification of endometrial carcinomas is? WHO 2020 Copy number high group, lack p53 mutations Copy number low group, have p53 mutations Tumors with CTNNB1 mutations have a good prognosis POLE ultramutated tumors have a good prognosis 1 out of 5 Please fill in the comment box below. Time is Up! Time's up Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...