Female Genital Tract- Uterus MCQs Posted on 4 May 2021 by pathologymcqs Welcome to your Female Genital Tract- Uterus MCQs-Sample 1. A 55-year-old woman has a hysterectomy for persistent bleeding. On gross examination you see a 2-cm polypoid mass with a villous surface. The cut surface is white, spongy and cystic. Microscopically the surface of the lesion has broad, dub-shaped papillae of stroma covered by proliferative phase endometrial cells. The stroma consists of bland cells that resemble fibroblasts and benign endometrial stromal cells. What is the diagnosis?AdenomyomaAtypical polypoid adenomaAdenofibromaBenign polypAdenomatoid tumor2. Which of the following can be seen in atypical hyperplasia?Architectural pattern may be simple or complex.Metaplastic changes may be present in any type of hyperplasia (particularly the morular variant of squamous metaplasia).True nuclear stratification (2-4 cells thick) with loss of polarity usually present and ofi:en more marked than in complex hyperplasia without atypia.Atypical cells tend to be enlarged; nuclear-cytoplasmic ratio is increased; nuclei large, hyperchromatic, and pleomorphic (tend to be more rounded than oval); nuclear membranes usually irregular·and thick; nucleoli prominentAll of the above3. According to the latest WHO classification of female genital tract tumors (2020), which of the following variants of leiomyoma is an addition?SymplasticFumarate hydratase deficientAnaplasticBizzarePleomorphic4. A 51 year old woman presented with vaginal bleeding and workup revealed a large uterine mass. Hysterectomy and bilateral salpingo-oophorectomy is performed. Pathology is consistent with a low grade endometrial sarcoma. Which of the following statements is false?CD10 is negative in tumor cellsER and PR positive in tumor cellsh-Caldesmon is negative in tumor cellsJAZF1-SUZ12 mutation is most commonly seen5. True statement about the recently proposed molecular classification of endometrial carcinomas is? WHO 2020Copy number high group, lack p53 mutationsCopy number low group, have p53 mutationsTumors with CTNNB1 mutations have a good prognosisPOLE ultramutated tumors have a good prognosis6 out of 5Please fill in the comment box below. Time is Up! Time's up Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading... Related Author: pathologymcqs Daily MCQ's and updates will be posted for various entrance exams View All Posts
