FGT pathology Welcome to your FGT pathology- Quiz 1. A 42-year female with a history of missed abortion 5 months back presents with lower abdominal pain . Her serum hCG level was slightly elevated. CT showed A solid mass in the lower uterine segment.The patient underwent TAH+BSO. Tumor shows no necrosis, on immunohistochemistry HSD3B and Ki67 positive > 10% cells and negative for p63 and cyclin E. What is the likely diagnosis. A) Placental site nodule B) Epithelial trophoblastic tumor C) Placental site trophoblastic tumor D) Exaggerated placental reaction 40. Which is true regarding the characteristics of type I ovarian tumors? A) TP53 mutation is common B) Slow growing and confined to ovary C) Arises from the tubal epithelium D) BRCA1/BRCA2 mutations may be present 3. A 74 year old woman with cystic intraabdominal mass, underwent hysterectomy with BSO. Grossly, a cystic ovarian mass is identified. Microscopy is shown in the image . What is the most likely diagnosis A. Sarcoma like mural nodule B. Serous cystadenoma C. Endometrioid adenocarcinoma D. Granulosa cell tumor 4. A 30 year old woman presented with heavy vaginal bleeding for 10 months. Biopsy findings shown in the picture above. Immunohistochemistry positive for CD99, Vimentin and FLI-1 but no EWSR1 rearrangements seen. What is the most likely diagnosis? A. Metastasis from Ewing's sarcoma B. Uterine PNET C. Lymphoma D. Synovial sarcoma 5. A 48 year old woman is diagnosed with a 6 cm adnexal mass arising from the broad ligament. She undergoes salpingo-oophorectomy. Microscopically, the tumor has a nodular appearance with low grade cells arranged in a sieve-like pattern and tightly packed tubules with eosinophilic secretions. No necrosis is seen. Mitotic activity is 1/10 high powered fields. The tumor cells are negative for PAX8 and positive for CD10. Which of the following is likely to be true? A. Final diagnosis is based on ancillary studies B. Minimal nuclear atypia and low mitotic rate are predictive of benign behavior C. Tumor originated from paramesonephric embryological remnants D. Tumor originated from mesonephric embryological remnants Time is Up! Time's up Share this:FacebookTelegramWhatsAppMoreLinkedInTwitterLike this:Like Loading...