Pathology MCQs for various entrance exams

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38. Which of the following is true regarding autoimmune gastritis?

A. Antibodies to H. Pylori are present

B. Can transform to type I carcinoid

C. Gastrin production is markedly decreased

D. Most commonly occurs in the gastric antrum

1 out of 10

All of the following conditions can result in gastric adenocarcinoma except?

Menetrier disease

Gastric adenomas

Gastritis cystica

Autoimmune gastritis

2 out of 10

Which of the following statements is false regarding MUTYH-related polyposis?

APC gene is involved in the pathogenesis

In contrast to familial adenomatous polyposis, MUTYH-associated polyposis fewer polyps are present

Colon cancer development is later in onset compared to familial adenomatous polyposis

It is an Autosomal recessive syndrome

3 out of 10

All of the following morphological features are included as graded variables in Sydney system for classification of gastritis except?

Atrophy

Inflammation

Intestinal metaplasia

Presence of granulomas

4 out of 10

All of the following heriditary polyposis syndromes are inherited in an Autosomal dominant fashion except?

Familial adenomatous polyposis

Turcot syndrome

Cronkchite Canada syndrome

Cowden syndrome

5 out of 10

Which is the most commonly mutated gene in sporadic colon cancer

MLH1

APC

MSH2

BRAF

6 out of 10

39. Which of the following is not a histologic feature of ulcerative colitis

A. Presence of pseudopolyps

B. Presence of multiple strictutes

C. Pseudopyloric epithelial metaplasia

D. Inflammation limited to the superficial mucosa and submucosa

7 out of 10

Which of the following is false regarding SDH- deficient GIST? ( WHO 2019 Digestive tract)

Has a female preponderance

Strong immunoreactivity for SDHB

Exclusively occurs in the stomach

Affects young adult population

8 out of 10

Which of the following is false regarding prognostic factors of GIST

Gastric GIST has a better prognosis.

Tumor rupture is also with a worse outcome

Kit exon 11 mutation is imatinib resistant

Tumor size > 10 cm is associated with a worse outcome.

9 out of 10

Which of the following gene mutations can be present in gastric clear cell sarcoma?

FLT3

STAT3

SMAD2

EWSR1

10 out of 10

GI Pathology quiz for pathology boards

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