1. Bone marrow biopsy from a 40-year-old man with acute myeloid leukemia (AML) shows a preponderance of hypergranular promyelocytes and bundles of Auer rods. Which one of the following is the most likely karyotype in his bone marrow metaphase cells?

2. Which one of the following chromosome abnormalities is associated with a poor prognosis in patients with MDS?

3. The following karyogram is representative of nine cells from a bone marrow study. In addition, a high hyperdiploidy clone was observed with a t(9;22)translocation, and molecular studies revealed an IKZF1 deletion. What is the most likely diagnosis?