Subtitle: Salivary gland pathology MCQs for NEET-SS, DM Oncopathology, FRCPath and board exams: pleomorphic adenoma, Warthin tumour, mucoepidermoid, adenoid cystic, acinic cell and secretory carcinoma, fusion genes and the Milan system, with 15 MCQs and a quick-review table.
Author: PathologyMCQ Editorial Board
Category: Endocrine Pathology
Last Updated: October 2026
Read Time: 6 minutes
At-a-Glance
- 15 MCQs with explanations on salivary gland tumours and cytology.
- Useful for NEET-SS, DM Oncopathology and Histopathology, oncopathology fellowships, FRCPath and American Board exams.
- Quick-review table of salivary tumour genetics and the Milan system.
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Test Yourself: 15 MCQs
Salivary gland pathology: 15 MCQs
Benign and malignant salivary tumours, fusions and the Milan system, with instant explanations.
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Quick Review
| Tumour | Genetics | Clue |
|---|---|---|
| Pleomorphic adenoma | PLAG1, HMGA2 | Chondromyxoid stroma, epithelial and myoepithelial cells |
| Mucoepidermoid carcinoma | CRTC1::MAML2 | Mucous, intermediate and epidermoid cells |
| Adenoid cystic carcinoma | MYB::NFIB (or MYBL1) | Cribriform, perineural invasion |
| Acinic cell carcinoma | NR4A3 activation | Zymogen granules, PAS-D positive |
| Secretory carcinoma | ETV6::NTRK3 | S100, mammaglobin, pan-TRK |
| Polymorphous adenocarcinoma | PRKD1 mutation or PRKD fusions | Palate, targetoid single-file |
| Hyalinising clear cell carcinoma | EWSR1::ATF1 | Clear cells, hyalinised stroma |
| Salivary duct carcinoma | HER2 amplification, AR | Comedonecrosis, apocrine; often ex PA |
| Category | Name |
|---|---|
| I | Nondiagnostic |
| II | Non-neoplastic |
| III | Atypia of undetermined significance |
| IVA | Neoplasm: benign |
| IVB | Salivary gland neoplasm of uncertain malignant potential (SUMP) |
| V | Suspicious for malignancy |
| VI | Malignant |
More Topics
Thyroid pathology MCQs → · Endocrine pathology MCQs → · Secretory carcinoma (ETV6::NTRK3) → · More pathology quizzes →
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- ❓Daily MCQ with explanations and streaks
- 🔬Virtual slides you pinch-zoom, with annotations
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References
- WHO Classification of Tumours Editorial Board. Head and Neck Tumours. 5th ed. IARC; 2022.
- Rossi ED, Faquin WC, eds. The Milan System for Reporting Salivary Gland Cytopathology. 2nd ed. Springer; 2023.
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