Subtitle: Thyroid pathology MCQs for NEET-SS, DM Oncopathology, FRCPath and board exams: thyroiditis, follicular adenoma and carcinoma, NIFTP, papillary carcinoma subtypes, medullary and anaplastic carcinoma and WHO 2022 high-grade tumours, with 15 MCQs and a quick-review table.
Author: PathologyMCQ Editorial Board
Category: Endocrine Pathology
Last Updated: October 2026
Read Time: 6 minutes
At-a-Glance
- 15 MCQs with explanations across thyroid pathology.
- Useful for NEET-SS, DM Oncopathology and Histopathology, oncopathology fellowships, FRCPath and American Board exams.
- Quick-review table of thyroid tumours and their drivers (WHO 2022).
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Test Yourself: 15 MCQs
Thyroid pathology: 15 MCQs
Thyroiditis, follicular lesions, papillary, medullary and anaplastic carcinoma (WHO 2022), with instant explanations.
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Quick Review
| Tumour | Driver | Clue |
|---|---|---|
| Papillary carcinoma, classic and tall cell | BRAF V600E | PTC nuclei, papillae, psammoma bodies |
| Follicular adenoma / carcinoma, NIFTP, invasive encapsulated follicular variant PTC | RAS, PAX8::PPARG | Follicular pattern; invasion defines carcinoma |
| Oncocytic carcinoma | Mitochondrial DNA and chromosomal losses | Oncocytes with capsular or vascular invasion |
| Medullary carcinoma | RET (germline in MEN2) | Calcitonin, amyloid |
| Poorly differentiated / differentiated high-grade | RAS, BRAF plus TERT, TP53 | Mitoses โฅ5/2 mmยฒ or necrosis |
| Anaplastic carcinoma | TP53, TERT, often BRAF | Elderly, rapid growth |
| Hyalinising trabecular tumour | PAX8::GLIS3 | Membranous MIB-1 |
| Cribriform-morular carcinoma | APC, CTNNB1 | FAP, nuclear ฮฒ-catenin |
More Topics
Bethesda 2023 thyroid cytology โ ยท Endocrine pathology MCQs โ ยท Salivary gland MCQs โ ยท More pathology quizzes โ
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Practise a slide and an MCQ every day, even when you are away from your desk.
- โDaily MCQ with explanations and streaks
- ๐ฌVirtual slides you pinch-zoom, with annotations
- ๐Your courses, notes and mocks in one place
References
- WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine Tumours. 5th ed. IARC; 2022.
- Baloch ZW, et al. Overview of the 2022 WHO classification of thyroid neoplasms. Endocr Pathol. 2022;33:27โ63.
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